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F4CP Making a High-Impact Impression
The Foundation for Chiropractic Progress has released details of its 2016 strategy, certain elements of which are already in play. The strategy includes ads, posters and other resources available to all F4CP members.
Dietary Fat and Prostate Cancer: An Important Update
K.M. Di Sebastiano and M. Mourtzakis published a review paper examining the role of dietary fat on prostate cancer development and progression late last year that does a stellar job of summarizing the available data on fat and prostate cancer.
Tailor-Made Knee Pain: The Sartorius Muscle
A patient was referred to my office after receiving treatment from various providers with no results. The patient was training for the Olympics as a marathon runner and was unable to run or walk without severe medial knee pain.
Targeting the Bad Apples in the Bunch
While everyone was focused on the conversion to ICD-10, the Office of Inspector General for Health and Human Services released a new report on chiropractic titled "CMS Should Use Targeted Tactics to Curb Questionable and Inappropriate Payments for Chiropractic Services."
Designing a Fitness Plan (Part 1)
It doesn't matter if you come to my practice for pain relief, weight loss, healthy aging or something else. The formula I talk about for each patient's fitness strategy is pretty much the same.
The Modern Application of Ancient Mei Rong
Chinese Medical Cosmetology (Mei Rong) has a well-documented and venerated history dating back to the Qin (221-206 BC) Dynasty.
Diagnose Sprain Injuries in MVA Cases With Dynamic X-Rays (Pt. 1)
Am I the only person to notice hospitals are doing a seemingly insufficient job lately in their initial radiological workup of motor vehicle accident (MVA) victims?
It's Time to Review
It is amazing to see the changes that are occurring in the acupuncture profession. Let's look at some of the news and events that have contributed to this growth and awareness.
Syncretism: Acupuncture and Public Health in Cuba
"Syncretism" is defined as a union of diverse tenets or practices. On a recent trip to Cuba designed to demonstrate the integration of Traditional Medicine and biomedicine, our group witnessed this union firsthand.
Chinese Herbs and Pulmonary Fibrosis: A Case Study
"Mary M."* recently celebrated her 90th birthday. Even the former sheriff dropped by to kiss the hand of this diminutive retired teacher, to honor the years she interpreted for him during interviews with Latinas and Latinos.
Mechanism: Experimental Approaches to Understanding Acupuncture, Part 1
The clinical benefits of acupuncture are difficult to ignore, but also can be difficult to explain to a Western audience. For nearly 50 years, relentlessly inquisitive scientists and physicians have been working toward a conceptual model to explain acupuncture.
Your Billing Questions Answered
I hear a lot of the following questions: I am afraid I may doing something illegal. I have heard I cannot have different fees for the same service.
Making Sense of an Increasingly Obvious Conclusion
Where's U.S. health care heading? Like it or not, the list of telltale signs is growing to a point that stands out to even the most myopic observer. Consider this list of facts as you look into the future of health care in the United States:
Which Way is the Energy Going? Are You Burning Yourself Out?
One of the simple methods that I use to define Yin/Yang theory to patients is to ask the question, "Which way is your energy going?"
The Concussion-Subluxation Complex
In the Aug. 1, 2014 issue of Dynamic Chiropractic, I reviewed some of the literature demonstrating the role of the chiropractic adjustment in post-concussive care.
One Size Does Not Fit All: Exercise and Nutrition According to Your Yin/Yang Body Type
There are countless new exercise and nutrition plans out there, emphasizing the latest ground-breaking research and claiming to revolutionize the way we view health.
Too Many to Remember: Tips to Revive Your Ortho / Neuro Test Skills
When I was at Palmer in the mid-1980s, we were given a set of notes in one of our diagnostic courses. The notes covered approximately 70 orthopedic and neurological tests for various regions of the body.
Footsteps of the Sages: An Apprenticeship with Dr. Kezhan Zhang
When I met Dr. Kezhen Zhang in May 2013, I was his translator and the integrity, creativity, and passion he demonstrated as a practitioner and advocate of the medicine convinced me to travel to Beijing to study with him.
Pro-Con: Swaddling for Newborns
The practice of swaddling has been used for thousands of years and was popular until the 1700s, when it was slowly abandoned by many cultures that considered it old-fashioned or barbaric.
Born to Energize the Human Spirit: Recollections of Sig Miller
Sig Miller, longtime executive director of the Association of New Jersey Chiropractors (ANJC), passed away on Sept. 17 after a long battle with cancer.
Acupuncture Rising: From Acupuncture Anesthesia to Assisted-IVF, Part 2
Acupuncture's cultural and historical roots go back to the emergence of Chinese civilization. For more than 2,000 years, acupuncture needling has been continuously practiced on the largest population in the world.
Omega-3 Fish Oil: An Underappreciated Element of Men's Health
As a clinician with many male patients -- and as a man myself -- I am all too aware of the fact that we like to convince ourselves that we are doing great, when that may be the farthest thing from the truth.
North Carolina Acupuncture Board Files Dry Needling Lawsuit
In early September, the NCALB filed a complaint against the North Carolina Board of Physical Therapy Examiners over the issue of dry needling, a form of acupuncture that uses solid needles to puncture the skin and muscle tissue to relieve pain.
August, 2005, Vol. 05, Issue 08
The Natural Effects of Melatonin
By John Upledger, DO, OMM
As manual therapists, it's vital that we continue to study the human organism - inside and out - to fully understand our role in helping individuals achieve optimal health and well-being.As part of that quest, I've been researching a helpful natural chemical called melatonin. This lipophilic indole, chemically known as 5-methoxy-N-acetyl-tryptamine, is a derivative of serotonin, which in turn is derived from the amino acid tryptophan.
Until recently, researchers thought melatonin was secreted only by the pineal gland. Since it was synthesized within and secreted by a gland, it became known as a hormone. Scientists have also speculated that melatonin was only secreted at night and primarily to induce sleep, and that artificial light could reduce the amount of melatonin secreted by the pineal gland. Since then, we've learned a lot more about the powers of melatonin. Yes, it's confirmed: The pineal gland is a major source of melatonin, which does indeed induce sleep. And yes, when the eyes take in artificial light, sleep is somewhat inhibited.
About 30 years ago we discovered that the appendix also generously synthesizes and secretes melatonin, which suggested that appendectomies might reduce melatonin levels. We've since found out that melatonin is also produced by the intestines, the fundus of the stomach, the testes, the spinal cord, the raphe nuclei of the brain stem, and the striatum areas of the brain. We now also understand that a significant amount of melatonin is synthesized within the body cells. Many of these melatonin molecules do not even leave their cells of origin, but instead remain inside them to protect them from being damaged by oxygen and nitrogen radicals and other toxicants.
You might even call melatonin a "double whammy" protector. After it neutralizes damaging reactive species, the metabolites that are produced in the process are even more effective at protecting the cells than the original melatonin molecules. In general, melatonin seems especially protective of DNA inside the nuclei and mitochondria. It also protects cell-membrane lipids and cytosol-contained proteins.
Personally, I believe every cell in our body contains some melatonin, whether it was produced in that cell or, less likely, entered through extracellular body fluids. Yet there are also other sites in the body with high levels of melatonin. The level of melatonin in the bile of the liver and gallbladder exceeds that of the blood and bone marrow. And the level of melatonin in cerebrospinal fluid (CSF) is much higher than that of the blood. In the CSF, melatonin is greatest in and around the third ventricle of the brain, probably because of the pineal-gland secretions. CSF melatonin levels are also greater at night, as is the pineal gland's production of melatonin. It's also interesting to note that the fluid in the Graafian follicle is higher than the blood level of melatonin.
Now let's look at some of the positive effects melatonin offers in specific dis-ease processes. Probably most important at this time is the fact that melatonin reduces degenerative activities in the brain, spinal cord and spinal nerve roots. Degeneration of these nerve tissues and cells often occur from the effects of reactive oxygen species and reactive nitrogen species, as well as excessive or prolonged inflammation.
Beta amyloid peptides (BAP) are metabolic byproducts of the degradation of amyloid precursor proteins (APP). When these proteins (which are normally part of cell membranes) are metabolized as they wear out and lose their functional abilities, they break down into BAP. When these peptides aren't effectively cleared away by the natural flushing of CranioSacral Therapy (CST) or other fluid-moving techniques, they can form plaques and tangles that cause neuronal dysfunction and death. The result? Increased tissue inflammation that leads to cerebral and/or spinal cord degeneration. The name of any resulting disease depends on the location of the degeneration. When it takes place in the hippocampus and cerebral forebrain, it's called Alzheimer's disease. When it takes place in the lower aspect of the brain (the substantia nigra), it's called Parkinson's disease.
Melatonin helps by neutralizing BAP to keep the peptides from forming disease-producing plaques and tangles. It also removes metals that may be involved in the plaques and tangles. These metals include cobalt (often found at higher levels with Alzheimer's disease) and aluminum. Occasionally, high levels of iron may damage the brain or spinal cord, while excessive copper may affect the central nervous system (CNS) in a similar way. Melatonin removes excess iron and copper as needed.
On the opposite side of the fence, melatonin may link up with zinc. This combination seems to enhance thymus-gland function and the whole immune system secondarily. When CNS neurons have been damaged, melatonin also promotes the production of neuronal growth factor, which may help reestablish neuronal circuits that have been injured or interrupted. (I have also had success dialoging with stem cells and getting them to replace damaged or dead neurons as needed.)
Other conditions I believe to be helped by melatonin: stroke damage; damage due to ionizing radiation; diabetic neuropathy; heavy-metal toxicities; non-metallic toxicities; viral infections; seizures; excitotoxicities; homocysteine damage; ischemic damage; reperfusion injury; degenerative CNS diseases, such as Alzheimer's, Parkinson's, multiple sclerosis, amyotrophic lateral sclerosis, senility and so on.
From a therapeutic perspective, I've found the following tactics helpful in enhancing melatonin effectiveness:
* I administer these in divided doses as tolerated by the client. Please note: The information presented here is strictly intended for educational purposes only, and is not to be construed as medical advice.
By continuing to explore the valuable role of melatonin in our bodies and by learning tools to enhance its effectiveness through complementary care, we give our clients more opportunities to enjoy good health, naturally.
Click here for previous articles by John Upledger, DO, OMM.
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