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The Kidney Official
The Kidney is known as the Official Who Controls the Waterways. In Western medical terms, a major function of the Kidneys is to filter the blood. Every day, a person's kidneys process about 200 liters of blood to sift out about two liters of waste and excess water.
Not Another Typical Drug Company Lawsuit
It's becoming more common to see drug manufacturers negotiate "false claims" settlements for millions and billions of dollars.1-2 Most of these settlements have to do with violations in the marketing of the drugs they produce and sell.
Advice for Young Doctors
When I began practice, I was just shy of my 25th birthday. I was young and I looked it. I had been told this would be a problem when starting a practice – and it was. Older patients often paused when they entered for care.
Healing With Simple, Healthy Food
When it comes to your health, there is no better way to take control and create positive outcomes than by focusing on diet and lifestyle. As chiropractors, you know the power that regular self-care has for your patients.
Spotlight on Acupuncture Research at IRCIMH
Acupuncture and Traditional Chinese Medicine were well-represented at the International Research Congress on Integrative Medicine and Health (IRCIMH)- 2014 which took place in Miami from May 13–16.
Inside Liver Failure, Cirrhosis and Cancer
The Liver belongs to Wood in Five Element Theory and is in charge of Dispersing and Expanding which means all the processing and detoxifying of harmful substances such as medications and chemicals require the efforts of the Liver.
Post-Concussion Patient Care: Relevance of the Chiropractic Adjustment
There is a widespread understanding within the profession of the general guidelines for care of the concussion patient. These include guidelines for physical and cognitive rest, return to normal activities and so forth.
The Gluteal-Knee Connection
The underlying causes of knee pain and dysfunction are rarely isolated to the knee. The knee is a relatively stable joint with limited intrinsic ability to adapt to aberrant motion.
Looking For Answers In Many Places
I am sure we have all heard the old adage: "When the only tool in your toolbox is a hammer, everything starts to look like a nail."
Healing With Hope
Ella is a Gulf War veteran and a survivor of military sexual trauma. Like hundreds of veterans, Ella was on 11 different medications for depression, anxiety, insomnia, irritable bowel syndrome and chronic pain.
Primary Lateral Sclerosis: A Condition With a Chiropractic Connection
Primary lateral sclerosis (PLS) is a slowly progressive, adult degenerative disease of the upper motor neurons characterized by progressive spasticity or stiffness. It is a clinical diagnosis that has been avoided because it is (largely) a diagnosis of exclusion.
Offline Marketing Techniques: Opportunities to Help Grow Your Business
In a world becoming increasingly dominated by connected devices, when we think of marketing, we often think of online and social media marketing. Considerable attention is given to Facebook and Twitter, as well as CPC [cost-per-click] advertising.
Resolving Medial Arch Suspicions: The Navicular Drop Test
Healthy feet have three distinct arches: medial longitudinal, lateral longitudinal and anterior transverse.
Best Practices for Website Success
If one asked 10 years ago whether a website was relevant I was the first to suggest no. Yet as the world moves increasingly towards electronic information there is a dire need to have a website for your practice. Your website is actually your electronic calling card.
Deciphering The New CMS 1500 Claim Form
Q: I am confused on using the new 1500 form, particularly Block 14 and Block 15. What is required and how do I properly fill these out? And do I actually have to use this new form or may I continue using the old version?
Super Bowl Chiropractor
With opening night of the 2014 National Football League season only a month away, what better time to talk to Dr. Jim Kurtz, team chiropractor for the defending Super Bowl champion Seattle Seahawks?
Looking Back: Abstracts From Chiropractic History
D.D. Palmer's Technique for the Posterior Apical Prominence; An Early Attempt to Achieve Consensus on Subluxation; Chiropractic Subject Headings: Past, Present and Future; Mabel Palmer: A History of Chiropractic That Almost Wasn't.
The Acupuncture Success Express
Time is passing very quickly these days. We are atoms half the way through the year of the horse. You could call it "horse racing season" for this profession. Perhaps it is time for reinvention during this time.
Hazards in the Environment Making Your Patients Sick
Working both separately and together, Western and Chinese medicine have many successes in the treatment of the myriad diseases that afflict human beings in modern times.
Talking to Skeptical MDs: "Just the Facts, Ma'am"
The first lesson in public speaking is to know your audience. This is particularly applicable when talking to skeptical medical doctors about chiropractic. You have to understand where they are coming from and speak the language they understand.
Getting Athletes Back in the Game: Low-Level Laser Therapy for Sports Injuries
Sports injury rehabilitation is all about getting back in the game quickly and with optimal health. A relatively new tool for the treatment of sports injuries is finding global success, and it is doing so in a fast, efficient way.
F4CP: New Campaign to Promote Chiropractic as a Career
The F4CP has announced a "targeted cooperative campaign" that will engage doctors of chiropractic and chiropractic students, as well as chiropractic colleges, chiropractic media, state associations and vendors, to encourage DCs to recommend a chiropractic career to patients, family and friends.
August, 2005, Vol. 05, Issue 08
The Natural Effects of Melatonin
By John Upledger, DO, OMM
As manual therapists, it's vital that we continue to study the human organism - inside and out - to fully understand our role in helping individuals achieve optimal health and well-being.As part of that quest, I've been researching a helpful natural chemical called melatonin. This lipophilic indole, chemically known as 5-methoxy-N-acetyl-tryptamine, is a derivative of serotonin, which in turn is derived from the amino acid tryptophan.
Until recently, researchers thought melatonin was secreted only by the pineal gland. Since it was synthesized within and secreted by a gland, it became known as a hormone. Scientists have also speculated that melatonin was only secreted at night and primarily to induce sleep, and that artificial light could reduce the amount of melatonin secreted by the pineal gland. Since then, we've learned a lot more about the powers of melatonin. Yes, it's confirmed: The pineal gland is a major source of melatonin, which does indeed induce sleep. And yes, when the eyes take in artificial light, sleep is somewhat inhibited.
About 30 years ago we discovered that the appendix also generously synthesizes and secretes melatonin, which suggested that appendectomies might reduce melatonin levels. We've since found out that melatonin is also produced by the intestines, the fundus of the stomach, the testes, the spinal cord, the raphe nuclei of the brain stem, and the striatum areas of the brain. We now also understand that a significant amount of melatonin is synthesized within the body cells. Many of these melatonin molecules do not even leave their cells of origin, but instead remain inside them to protect them from being damaged by oxygen and nitrogen radicals and other toxicants.
You might even call melatonin a "double whammy" protector. After it neutralizes damaging reactive species, the metabolites that are produced in the process are even more effective at protecting the cells than the original melatonin molecules. In general, melatonin seems especially protective of DNA inside the nuclei and mitochondria. It also protects cell-membrane lipids and cytosol-contained proteins.
Personally, I believe every cell in our body contains some melatonin, whether it was produced in that cell or, less likely, entered through extracellular body fluids. Yet there are also other sites in the body with high levels of melatonin. The level of melatonin in the bile of the liver and gallbladder exceeds that of the blood and bone marrow. And the level of melatonin in cerebrospinal fluid (CSF) is much higher than that of the blood. In the CSF, melatonin is greatest in and around the third ventricle of the brain, probably because of the pineal-gland secretions. CSF melatonin levels are also greater at night, as is the pineal gland's production of melatonin. It's also interesting to note that the fluid in the Graafian follicle is higher than the blood level of melatonin.
Now let's look at some of the positive effects melatonin offers in specific dis-ease processes. Probably most important at this time is the fact that melatonin reduces degenerative activities in the brain, spinal cord and spinal nerve roots. Degeneration of these nerve tissues and cells often occur from the effects of reactive oxygen species and reactive nitrogen species, as well as excessive or prolonged inflammation.
Beta amyloid peptides (BAP) are metabolic byproducts of the degradation of amyloid precursor proteins (APP). When these proteins (which are normally part of cell membranes) are metabolized as they wear out and lose their functional abilities, they break down into BAP. When these peptides aren't effectively cleared away by the natural flushing of CranioSacral Therapy (CST) or other fluid-moving techniques, they can form plaques and tangles that cause neuronal dysfunction and death. The result? Increased tissue inflammation that leads to cerebral and/or spinal cord degeneration. The name of any resulting disease depends on the location of the degeneration. When it takes place in the hippocampus and cerebral forebrain, it's called Alzheimer's disease. When it takes place in the lower aspect of the brain (the substantia nigra), it's called Parkinson's disease.
Melatonin helps by neutralizing BAP to keep the peptides from forming disease-producing plaques and tangles. It also removes metals that may be involved in the plaques and tangles. These metals include cobalt (often found at higher levels with Alzheimer's disease) and aluminum. Occasionally, high levels of iron may damage the brain or spinal cord, while excessive copper may affect the central nervous system (CNS) in a similar way. Melatonin removes excess iron and copper as needed.
On the opposite side of the fence, melatonin may link up with zinc. This combination seems to enhance thymus-gland function and the whole immune system secondarily. When CNS neurons have been damaged, melatonin also promotes the production of neuronal growth factor, which may help reestablish neuronal circuits that have been injured or interrupted. (I have also had success dialoging with stem cells and getting them to replace damaged or dead neurons as needed.)
Other conditions I believe to be helped by melatonin: stroke damage; damage due to ionizing radiation; diabetic neuropathy; heavy-metal toxicities; non-metallic toxicities; viral infections; seizures; excitotoxicities; homocysteine damage; ischemic damage; reperfusion injury; degenerative CNS diseases, such as Alzheimer's, Parkinson's, multiple sclerosis, amyotrophic lateral sclerosis, senility and so on.
From a therapeutic perspective, I've found the following tactics helpful in enhancing melatonin effectiveness:
* I administer these in divided doses as tolerated by the client. Please note: The information presented here is strictly intended for educational purposes only, and is not to be construed as medical advice.
By continuing to explore the valuable role of melatonin in our bodies and by learning tools to enhance its effectiveness through complementary care, we give our clients more opportunities to enjoy good health, naturally.
Click here for previous articles by John Upledger, DO, OMM.
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