resourcesABOUT MT AUTHOR GUIDELINES CLASSIFIEDS EDITORIAL CALENDAR MEDIA GUIDE MASSAGE MART SCHOOLS & EDUCATION FEEDBACK
Epigenetics: The Western Science Supporting Essence
Since the days of Darwin, western medicine has touted that our genes were set in stone, that our genetics were our destiny. We were told that the diseases that ran in our family were likely coming to us as well.
AAAOM – The Beginning of the End (Part II)
In 2012, the AAAOM board members met in Chicago for their annual meeting. The goal was to come to a consensus on a long list of issues the AAAOM needed to work on including a functional board and budget.
Green Tea Catechins Lower PSA, Other Biomarkers in Men With Localized Prostate Cancer
A 2006 study (Cancer Research) was the first human investigation to show that green tea catechins (GTC) are highly effective in reversing premalignant prostate lesions (high-grade prostate intra-epithelial neoplasia), an established precursor to prostate cancer.
News in Brief
Hamm Elected New President of the ACA; WFC / ACC 2014 Education Conference: Call for Papers; F4CP Recognizes Standard Process as $1 Million Supporter; Texas Chiro. College Begins Search for New President; League of Chiropractic Women Hosts Women's Success Summit.
Collaboration for a Cause
The Patient Protection and Affordable Care Act strongly encourages the formation of multidisciplinary practitioner teams called Patient Centered Medical Homes (PCMHs) and Accountable Care Organizations (ACOs).
Get That Shoulder to Move: Restoring Internal Rotation
How many times have you mobilized, performed ART, Graston, FAKTR and PIR, and stripped a patient's posterior capsule, yet on re-exam, discovered it was still blocked?
Leaving a Lasting Legacy: Donna Liewer
For the past 31 years, Donna Liewer has been on a personal mission "to comfort the afflicted and afflict the comfortable." In her role as executive director of the Federation of Chiropractic Licensing Boards, Liewer has accomplished that and much, much more.
Why DCs Need to Understand the Principles of "Inclusive Design"
In the past few columns, I've written about the negative effects of prolonged sitting at work. I've attempted to make the point that prolonged sitting (or prolonged standing) takes a toll on workers. Now let's discuss a related issue: the concept of "inclusive design."
Chiropractic Prevents ADHD? Research Shows...
Now that I have your attention, let me tell you what the latest study actually states. As you may have noticed, research over the past few years has begun to reveal that acetaminophen (the primary ingredient in Tylenol) is not as safe as once thought.
Stress in the Modern Age: Impact on Homeostasis and What You Can Do (Part 1)
In 1926, Hans Selye first used the word stress in a biological context, referring to the nonspecific response of the body to any demand placed upon it.
AAAOM – Making Promises They Can't Keep
When the AAAOM first formed in 2007, their mission was clear: to support the profession through education, resources and legislative advocacy. The first years of the organization were filled with promise and hope.
One and Done: Keeping Patients From Vanishing After Just One Appointment
What happened to my 3:30 p.m. ROF? They may have rescheduled, but there are two common answers no one wants to hear: 1) "She called to cancel. I tried to get her to reschedule, but she refused." 2) "She no-showed.
Resilience is the New Longevity
Sometimes we must enter a room through one door and not another, even though they both lead into the same space. I am talking now of the recent cachet with the concept of "resilience" regarding health, chronic pain and longevity.
Flexion-Intolerant Lower Back Pain (Pt. 3): Mobilization & Soft-Tissue Treatment
What is the biggest challenge to the chiropractor in treating discogenic pain? You have to completely reframe the purpose of your manipulation. It is rarely about unlocking a stuck segment at the disc involvement level; it is not about putting a joint back in alignment.
Successful Strategies in Integrating Acupuncture and Shiatsu in a Hospital Oncology Program
Colleagues from the Network of Researchers in Public Health in CAM recently published an article of interest to our Traditional Asian Medicine community.
Monoculture of the Mind: Part II
Cases are built within boundaries. Such bounds may be a program, event, activity or individuals. In this instance, a medical case has boundaries that include clinical interactions that are comprised of history, signs, symptoms, diagnoses, treatment plans and treatments.
Steven Rosenblatt: Birthing A Cross-Cultural Acupuncture Profession
The existence of a cross-cultural acupuncture profession in the United States, one that is legalized, licensed, supported by formalized, academic training and inclusive of non-Asian practitioners, is an important part of the medical landscape in this country and is responsible for improving the lives of hundreds of thousands of Americans.
What is a Discipline in Medicine?
In my now prolonged dialogue with physicians, one question emerges with enough regularity to deserve mention and naming: what is a discipline?
Risk Factors for Heel Problems
Heel pain and gait disability are common occurrences in adults, often the result of thinning heel pads and a lifetime of exposure to heel-strike shock. One condition experienced by many people is plantar fasciitis.
The Healing Properties of Light: An Interview With Researcher Anna Cocliovo
This interview is with Anna Cocliovo, a light researcher and Acupuncturist in Arizona. During my own research in light, I came across the article she published for the American Journal of Acupuncture and sought her out as a result.
Creating Child-Friendly Clinics with ABT
The Zurich Dojo was scattered with toy ducks, dolls, trains, exercise balls and teddy bears during my recent pediatric workshop.
Are You Guilty of Paternalism in Your Approach to Patient Care?
Einstein is purported to have said, "When a man sits with a pretty girl for an hour, it seems like a minute. But let him sit on a hot stove for a minute and it's longer than any hour. That's relativity." In some way, everything is relative to one's point of view.
August, 2005, Vol. 05, Issue 08
The Natural Effects of Melatonin
By John Upledger, DO, OMM
As manual therapists, it's vital that we continue to study the human organism - inside and out - to fully understand our role in helping individuals achieve optimal health and well-being.As part of that quest, I've been researching a helpful natural chemical called melatonin. This lipophilic indole, chemically known as 5-methoxy-N-acetyl-tryptamine, is a derivative of serotonin, which in turn is derived from the amino acid tryptophan.
Until recently, researchers thought melatonin was secreted only by the pineal gland. Since it was synthesized within and secreted by a gland, it became known as a hormone. Scientists have also speculated that melatonin was only secreted at night and primarily to induce sleep, and that artificial light could reduce the amount of melatonin secreted by the pineal gland. Since then, we've learned a lot more about the powers of melatonin. Yes, it's confirmed: The pineal gland is a major source of melatonin, which does indeed induce sleep. And yes, when the eyes take in artificial light, sleep is somewhat inhibited.
About 30 years ago we discovered that the appendix also generously synthesizes and secretes melatonin, which suggested that appendectomies might reduce melatonin levels. We've since found out that melatonin is also produced by the intestines, the fundus of the stomach, the testes, the spinal cord, the raphe nuclei of the brain stem, and the striatum areas of the brain. We now also understand that a significant amount of melatonin is synthesized within the body cells. Many of these melatonin molecules do not even leave their cells of origin, but instead remain inside them to protect them from being damaged by oxygen and nitrogen radicals and other toxicants.
You might even call melatonin a "double whammy" protector. After it neutralizes damaging reactive species, the metabolites that are produced in the process are even more effective at protecting the cells than the original melatonin molecules. In general, melatonin seems especially protective of DNA inside the nuclei and mitochondria. It also protects cell-membrane lipids and cytosol-contained proteins.
Personally, I believe every cell in our body contains some melatonin, whether it was produced in that cell or, less likely, entered through extracellular body fluids. Yet there are also other sites in the body with high levels of melatonin. The level of melatonin in the bile of the liver and gallbladder exceeds that of the blood and bone marrow. And the level of melatonin in cerebrospinal fluid (CSF) is much higher than that of the blood. In the CSF, melatonin is greatest in and around the third ventricle of the brain, probably because of the pineal-gland secretions. CSF melatonin levels are also greater at night, as is the pineal gland's production of melatonin. It's also interesting to note that the fluid in the Graafian follicle is higher than the blood level of melatonin.
Now let's look at some of the positive effects melatonin offers in specific dis-ease processes. Probably most important at this time is the fact that melatonin reduces degenerative activities in the brain, spinal cord and spinal nerve roots. Degeneration of these nerve tissues and cells often occur from the effects of reactive oxygen species and reactive nitrogen species, as well as excessive or prolonged inflammation.
Beta amyloid peptides (BAP) are metabolic byproducts of the degradation of amyloid precursor proteins (APP). When these proteins (which are normally part of cell membranes) are metabolized as they wear out and lose their functional abilities, they break down into BAP. When these peptides aren't effectively cleared away by the natural flushing of CranioSacral Therapy (CST) or other fluid-moving techniques, they can form plaques and tangles that cause neuronal dysfunction and death. The result? Increased tissue inflammation that leads to cerebral and/or spinal cord degeneration. The name of any resulting disease depends on the location of the degeneration. When it takes place in the hippocampus and cerebral forebrain, it's called Alzheimer's disease. When it takes place in the lower aspect of the brain (the substantia nigra), it's called Parkinson's disease.
Melatonin helps by neutralizing BAP to keep the peptides from forming disease-producing plaques and tangles. It also removes metals that may be involved in the plaques and tangles. These metals include cobalt (often found at higher levels with Alzheimer's disease) and aluminum. Occasionally, high levels of iron may damage the brain or spinal cord, while excessive copper may affect the central nervous system (CNS) in a similar way. Melatonin removes excess iron and copper as needed.
On the opposite side of the fence, melatonin may link up with zinc. This combination seems to enhance thymus-gland function and the whole immune system secondarily. When CNS neurons have been damaged, melatonin also promotes the production of neuronal growth factor, which may help reestablish neuronal circuits that have been injured or interrupted. (I have also had success dialoging with stem cells and getting them to replace damaged or dead neurons as needed.)
Other conditions I believe to be helped by melatonin: stroke damage; damage due to ionizing radiation; diabetic neuropathy; heavy-metal toxicities; non-metallic toxicities; viral infections; seizures; excitotoxicities; homocysteine damage; ischemic damage; reperfusion injury; degenerative CNS diseases, such as Alzheimer's, Parkinson's, multiple sclerosis, amyotrophic lateral sclerosis, senility and so on.
From a therapeutic perspective, I've found the following tactics helpful in enhancing melatonin effectiveness:
* I administer these in divided doses as tolerated by the client. Please note: The information presented here is strictly intended for educational purposes only, and is not to be construed as medical advice.
By continuing to explore the valuable role of melatonin in our bodies and by learning tools to enhance its effectiveness through complementary care, we give our clients more opportunities to enjoy good health, naturally.
Click here for previous articles by John Upledger, DO, OMM.
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